Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is La Paz (56% of total searches to Bolivia). The next most popular destinations are Uyuni (28%) and Rurrenabaque (11%). Searches for hotels in Santa Cruz de la Sierra (6%) are also popular.
Based on KAYAK hotel searches, the most popular region to stay in Bolivia is Potosí. La Paz and Santa Cruz are also very popular.