Putting you within a 10-minute drive of Parque Nacional and National Center of Art and Culture, Casa 69 features a rooftop terrace and offers an airport pick-up service (available on request) for USD 40 per person. Free perks include WiFi and continental breakfast daily between 7 AM and 10 AM. There's also a garden, and rooms offer refrigerators and minibars.
Cons: When we showed up at 2:30 in the afternoon we were astonished to discover that they had given our room away even though we had paid a week in advance. They did however pay for and take us to Hotel 1492 which met our needs and was in a better neighborhood.
Pros: Clean, friendly, secure entry, free breakfast/wifi/computer, not too far from everything, helpful.
Cons: Near train track, but only runs Mon-Fri.