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Stay at the Comfort Inn hotel in Tupelo, MS to get rested and ready for anything. Our smoke-free hotel is near Tupelo Buffalo Park and Zoo, the National Fish Hatchery, Natchez Parkway, Tupelo National Battlefield, Lyric Theatre and the Tupelo Automobile Museum. Our hotel offers free WiFi, free breakfast, a seasonal outdoor pool, an exercise room and a free weekday newspaper. Rest and relax in a hotel room which features a flat-screen TV, hair dryer, coffee maker, desk and more. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.